Clemson and Troy will play Sept. 10, 2016, both schools announced Wednesday.
This will be the second game between the two schools. Clemson overcame a 16-13 halftime deficit to beat Troy 43-19 in the 2011 season opener at Clemson.
Clemson earlier announced it would play Georgia, South Carolina, Georgia State and Coastal Carolina as nonconference opponents in 2014. Two of the nonconference games in 2015 are Notre Dame and South Carolina.