Favre, who never has won in Nashville, has walked out of 31 NFL stadiums triumphant, tying him with Miami Dolphins legend Dan Marino for victories at the most venues.
Steve McNair is third with 30 stadiums. Joe Montana and Vinny Testaverde are tied for fourth with 28.
If he can't knock off the unbeaten Titans, Favre will have another opportunity to chalk up a new building Dec. 21. The Jets visit Qwest Field to play the Seattle Seahawks.