Williams is in his first game back after serving a four-game suspension for violating the NFL's policy on performance-enhancing substances. His return is a boost for the Bengals' running game.
Cincinnati, though, won't have nickel back Kelly Jennings (hamstring), who was scratched. The Bengals' other inactives are: offensive lineman Clint Boling, receiver Ryan Whalen, tight end Colin Cochart, linebacker Dontay Moch, tackle Anthony Collins and safety Robert Sands.
For the Jaguars, defensive end Aaron Kampman is inactive along with running back Montell Owens, wide receiver Kassim Osgood, cornerback Derek Cox, safety Courtney Green, offensive lineman Jason Spitz and tight end Zach Miller.