Jake TrotterSam Khan Jr. 41d

Big 12 Week 2 picks: Who wins the Oklahoma-Ohio State showdown?

Here are our Week 2 Big 12 picks (all times ET). Visit our college football PickCenter page for additional information on these games and many more.

No. 11 Oklahoma State at South Alabama, 8 p.m. ET Friday (ESPN2/WatchESPN)

Trotter: Past Oklahoma State teams might struggle on the road on a Friday against a non-Power 5 opponent. But these are not those Cowboys. Oklahoma State 51, South Alabama 16

Khan: The Cowboys won't mess around and will make quick work of the Jaguars. Oklahoma State 48, South Alabama 10

No. 23 TCU at Arkansas, 3:30 p.m. Saturday (CBS)

Trotter: With KaVonate Turpin firmly back in the fold, the Horned Frogs produce enough plays to land the Big 12 a win over the SEC. TCU 28, Arkansas 27

Khan: No Power 5 team has won more road games the past 10 seasons than Gary Patterson's Horned Frogs (37-12). They'll make it 38. TCU 34, Arkansas 24

No. 5 Oklahoma at No. 2 Ohio State, 7:30 p.m. Saturday (ABC/WatchESPN)

Trotter: Behind Baker Mayfield, the Sooners hang tough. But without the weapons from last season around him, Ohio State escapes with a victory. Ohio State 35, Oklahoma 31

Khan: Beating the Buckeyes in their backyard with a first-time head coach is a tough ask. The Sooners have the better quarterback in this matchup, but that alone won't be enough. Ohio State 27, Oklahoma 24

Iowa at Iowa State, 12 p.m. Saturday (ESPN2/WatchESPN)

Trotter: The Cyclones play well, but Iowa’s defense proves the difference in another fourth-quarter CyHawk game. Iowa 22, Iowa State 14

Khan: The Hawkeyes suffocated Wyoming quarterback (and highly regarded draft prospect) Josh Allen last week, and they'll keep this one low-scoring en route to a win over the Cyclones. Iowa 20, Iowa State 10

OTHER GAMES

East Carolina at West Virginia, 12 p.m. Saturday (FS2)

Trotter: West Virginia 41, East Carolina 16

Khan: West Virginia 55, East Carolina 10

Charlotte at No. 19 Kansas State, 12 p.m. Saturday

Trotter: Kansas State 45, Charlotte 10

Khan: Kansas State 52, Charlotte 7

San Jose State at Texas, 3:30 p.m. Saturday (Longhorn Network)

Trotter: Texas 34, San Jose State 17

Khan: Texas 44, San Jose State 20

Central Michigan at Kansas, 4 p.m. Saturday

Trotter: Kansas 27, Central Michigan 24

Khan: Kansas 37, Central Michigan 27

UT San Antonio at Baylor, 8 p.m. Saturday

Trotter: Baylor 24, UTSA 20

Khan: Baylor 30, UTSA 24

RECORDS

Trotter: 7-3

Khan: 8-2

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