Brandon Kinnie caught his second touchdown pass of the day, this one from Cody Green, and the Huskers added another on the next possession to put Nebraska up 31-3 early in the third quarter.
Rex Burkhead, a running back, threw his second touchdown pass of the day to take the four-touchdown lead.
That means the Buffaloes won't be able to lean heavily on running back Rodney Stewart, their best offensive weapon.
He'll still get plenty of touches, but quarterback Cody Hawkins is going to have to bring back the Buffs. The chances of that happening: slim.
Hawkins is 1-of-11 today, and his only completion came on a 26-yard pass on a pitch-and-passback trick play that spurred Colorado's only scoring drive.
That's no surprise against a Nebraska pass defense that entered today's game ranked No. 2. DeJon Gomes picked off Hawkins second pass of the third quarter, and Eric Hagg picked off another on his first of the next drive.
Good luck finding a team that wins a game--or is even in a game--while completing more passes to the opposing secondary than their own team.
Also notable: Colorado senior receiver Scotty McKnight has caught a pass in every game of his career, a streak of 48 consecutive games. He has been held without a catch so far today.
Nebraska fans, it's probably safe to stop worrying about having to cancel your hotel rooms in Dallas. Instead, tune into Bedlam (ABC, 8 p.m. ET) on Saturday night to learn who you'll see in Cowboys Stadium next week.