Senior defensive end Frank Alexander will be wearing Oklahoma linebacker Austin Box's No. 12 jersey on Saturday when the No. 1 Sooners take on No. 5 Florida State in Tallahassee.
Each Friday, Oklahoma plans to announce which player will wear Box's jersey as a tribute.
Box, who would have been a senior, died on May 19.
"I think it's a neat way to help (parents) Craig and Gail and their family. I think when you lose somebody tragically ... or a family member, I think one of the things we fear the most is people forgetting and just kind of sweeping it under the rug," said defensive coordinator Brent Venables, Box's former position coach at linebacker. "I think this is a terrific opportunity for us to help them as they continue to try to grieve and remember Austin the right way."