Posted by ESPN.com's Adam Rittenberg
1. Daryll Clark's response -- The Penn State quarterback took the blame for the Iowa loss and admits he's struggling right now. There has also been some ridiculous talk about replacing Clark with Pat Devlin. Clark shouldn't have to worry about his job, but he needs to get on track again against a woeful Indiana defense that has been hit hard by injuries in the secondary. This is the perfect game for Clark and the Nittany Lions to revive the big-play attack.
2. Ohio State defense vs. Juice Williams -- Williams toyed with the Buckeyes last fall in Columbus, throwing four touchdown passes and racking up 70 rush yards. He almost single-handedly ran out the final eight minutes to preserve a 28-21 upset. You can bet Malcolm Jenkins, James Laurinaitis and Ohio State's other defenders are itching to face Williams again in Champaign (ESPN, noon ET). Ohio State's defense is hitting its stride, but Williams will provide a good test.
3. Bret Bielema and Tim Brewster -- Something is bound to happen in the already simmering Wisconsin-Minnesota rivalry, and it will be interesting to see what the two head coaches say and do during and after Saturday's game. Bielema's dash to midfield after last year's Wisconsin win made waves this week, and Brewster has already declared Wisconsin as Minnesota's top rival. There should be some fireworks in Madison (ABC, 3:30 p.m.).
4. Makeshift offensive backfields at the Big House -- Both Northwestern and Michigan are dealing with injuries at quarterback and running back heading into Saturday's matchup (ESPN2, noon ET). Given both teams' problems with turnovers this season, the group that takes better care of the football likely comes out with the win. Michigan quarterback Nick Sheridan tries to build off a strong performance last week in his second straight start, while Northwestern senior quarterback C.J. Bacher likely will return to the field after sitting out the past two weeks with a hamstring injury. Michael Shaw (Michigan) and Stephen Simmons (Northwestern) likely get the starts at running back.
5. Illinois tries to continue crazy pattern -- Since Sept. 13, Illinois has alternated wins and losses. It's not what head coach Ron Zook had in mind, but he wouldn't mind if it continued Saturday against No. 11 Ohio State. Illinois lost last week against Western Michigan and needs a win to get bowl eligible. The Illini usually play the Buckeyes tough, but Ohio State has won 14 straight Big Ten road games.
6. Purdue's quarterback situation -- Fifth-year senior Curtis Painter should return in some form at Iowa, but redshirt freshman Justin Siller is expected to start for the Boilermakers. Head coach Joe Tiller hinted at having a quarterback rotation, with Painter being used for the two-minute drill. The quarterbacks' differing skill sets could present some problems for Iowa, but both players will need to perform well to give Purdue a chance for the upset.
7. Minnesota tries to survive without Eric Decker -- The Gophers' offense was downright awful last week, and they'll be without star wide receiver Eric Decker (high ankle sprain) at Wisconsin. Freshmen Brandon Green and Brodrick Smith and sophomore Ralph Spry will have to step up, but perhaps more important, Minnesota must generate a running game outside of quarterback Adam Weber.
8. Derrick Williams -- If Penn State had held on to beat Iowa, Williams would have been a big story. Penn State used Williams in the "Wildcat" formation, in part to protect Clark, and the senior showcased his speed and versatility. In addition to running for a touchdown, Williams completed a 23-yard pass to Mickey Shuler for Penn State's only play of longer than 20 yards. The Lions likely will continue to expand Williams' role and maximize his versatility against Indiana.
9. Shonn Greene -- Expect to see the Iowa junior running back on this list for the rest of the season. He's just that good, and I don't think we'll see him in college next fall. Greene aims for his 11th consecutive 100-yard rushing game against Purdue, which ranks 90th nationally in rush defense (172.8 ypg). He got a bit banged up on a fourth-quarter touchdown run last week against Penn State but is expected to be fine for Saturday's game.
10. Michigan's final home appearance -- The Wolverines won't be going bowling, but a second straight win and a favorable send-off for the seniors would dull the pain for their fans, who have booed quite a bit this season. Obviously, an upset next week in Columbus would be bigger for the Wolverines, but another victory against a team with a winning record will help matters.