1. EJ Manuel's consistency: Speaking to reporters after his 17-for-22 performance in Thursday's practice, Manuel stressed how he wanted to be more consistent and to carry over his successes from one practice (or game) to the next. He'll have a chance to do that Saturday. It's a similar story to last season. He completed 69 percent of his passes in Week 2, only to see his rate drop to the mid-40s in Weeks 3 and 4. Likewise, he posted a 71.4 rate in Week 11 before dropping down to the mid-50s the next two games. Manuel completed 69 percent of his throws in last Friday's game and 77 percent in Thursday's practice. Staying in that general range Saturday will suggest an improvement over his inconsistencies from last season.
2. Sammy Watkins' strides: If Manuel is storyline No. 1A with the Bills, then Watkins is No. 1B. Outside of his early drop in Wednesday's session, Watkins had another strong week of practice. Last week, it translated over into the game, with Manuel finding his top receiver three times for 21 yards. The two are likely to see more playing time together Saturday -- potentially through the first half -- so there should more opportunities to build chemistry in a live game setting. We've yet to see the duo stretch the field vertically in the preseason. Perhaps that will change Saturday.
3. Can defense maintain its pace? Outside of the Panthers' early touchdown drive, the Bills' first-team defense hasn't allowed more than 5 total yards on any drives this preseason. They've been downright smothering and it starts with the defensive line. They'll have a longer run in Saturday's game and a tougher opposing quarterback in Ben Roethlisberger. Does the defense continue to hold up well, or are some holes exposed? Our attention will be on the cornerbacks, especially Stephon Gilmore's potential matchup with Antonio Brown. Expect Roethlisberger to test that one early.