Here's our best guess at who those may be:
S Jairus Byrd -- Is doubtful with a foot injury after being limited in practice all week. Byrd has plantar fasciitis, and head coach Doug Marrone said the condition leaves Byrd's status as day to day.
CB Brandon Burton -- Claimed off waivers last weekend, Burton may need more time to acclimate to the Bills' system before seeing game action.
CB Stephon Gilmore -- Has already been declared out with a fractured wrist.
G/C Doug Legursky -- Has already been declared out with a knee injury.
K Dustin Hopkins -- Has already been declared out with a right groin strain.