Watkins caught passes from former Ohio State quarterback Kenny Guiton, who is a non-roster tryout this weekend, during the hour-long session that included mostly light positional drills.
"[He was] smooth coming in and out of the break. Obviously he can make the catches, makes nice catches," coach Doug Marrone said of Watkins' first practice.
That, of course, is just what the Bills expected to see. Anything less would be alarming.
"He's a first-round draft pick. If I came out here and he dropped five balls and he fell down five [or] 10 times, we'd be pissed. Crying," Marrone said, laughing.
"First day, I think it went pretty good overall," Watkins said. "Still have a lot of things to work on."
Watkins did not take part in special-teams drills Saturday, instead receiving one-on-one instruction from offensive coordinator Nate Hackett and wide receivers coach Rob Moore:
Sammy Watkins working off to side with OC Nate Hackett and WRs coach Rob Moore. Rest of WRs in different drill: pic.twitter.com/xQQb6JwvZY— Mike Rodak (@mikerodak) May 17, 2014
The Bills' rookie minicamp will continue through Monday. Watkins will begin working with starting quarterback EJ Manuel during organized team activities later this month.