Soto went on the disabled list with a sprained right shoulder and Lee was put on the bereavement list.
Castillo and Hoffpauir had difficulty with their airline connection and arrived at 6:15 p.m. local time, just an hour before the game was to begin.
Interim Cubs manager Alan Trammel inserted Hoffpauir in the three-hole, playing first base against two-time Cy Young Award winner Tim Lincecum.
“I wanted to put him in there,” Trammel said. “If the flight would have landed like it should have been, it would have been easy. Take your fly balls, your ground balls and get your regular [batting practice] in there. But everybody’s heard the stories about guys being called up at the last minute with no time to think about it. That’s what we’re doing.”
Trammel said he talked to Lou Piniella on Tuesday and the Cubs manager plans to rejoin the team in St. Louis on Friday. Piniella and his family are working on finding proper caregivers for his 90-year-old mother, who has been in and out of the hospital in the last few weeks.
“He kind of laid down the law [about his mother’s care],” Trammel said. “Lou’s going to take care of her. It’s been a tough go for Lou the last few weeks.”
Lee’s bereavement list status means that he’s not allowed to play in a game for 72 hours. The plan right now is for Lee to travel to St. Louis with the team on Thursday night. Lee’s grandfather has been seriously ill and the Cubs first baseman traveled up to Sacramento, Calif. to be with him.
Soto said that he had a cortisone shot in his right shoulder to relieve the pain from his shoulder sprain. Soto received the injection on Saturday and he said the pain was most apparent when he swings the bat, rather than throwing the baseball.
“Today is the third day after [the shot]. So a couple more days and I’ll be ready,” said Soto, who will not be eligible to come off the disabled list until August 23.
Trammel said in his pregame press gathering that it’s obvious by the team’s disappointing season so far that some players won’t be back in 2011.
“When things are tough you have to keep pushing,” Trammel said. “You can either quit or keep pushing. The first one isn’t an option. We had a nice ballgame yesterday. I like the effort, but it’s still a loss.”