Rapid Reaction: Reds 4, Cubs 1

CINCINNATI -- The Cincinnati Reds beat the Chicago Cubs 4-1 on Wednesday night at Great American Ball Park. It was the fifth straight win for the Reds and the sixth straight loss for the Cubs.

Here’s a quick look at the game:

How it happened: The Reds finally got to Cubs starter Dallas Beeler for three runs with two outs in the bottom of the fifth to break a 1-1 tie. Billy Hamilton had the go-ahead hit for the Reds with a two-out triple past center fielder Justin Ruggiano to drive in Zack Cozart from second base. Cozart had lofted a single into right-center, just out of the reach of second baseman Arismendy Alcantara, and moved to second on a sacrifice by pitcher Alfredo Simon.

Skip Schumaker followed Hamilton’s triple with a walk and Brandon Phillips and Jay Bruce each singled in a run to cap a three-run inning. The Reds took a 1-0 lead in the bottom of the second when third baseman Ramon Santiago belted a two-out double into the gap in right-center to plate first baseman Brayan Pena from first base. Santiago was thrown out trying to stretch the double into a triple. Pena drew a two-out walk ahead of Santiago. Anthony Rizzo tied it in the third with his 20th home run of the season, a towering shot down the line in right on a 2-0 pitch. But Chicago never got another runner as far as second base.

What it means: The Cubs have followed a four-game winning streak with what is now a six-game losing streak and four games to go before the All-Star break.

Beeler’s night: Beeler, a rookie right-hander, held the Reds to two hits and a run through four innings, but a three-run fifth inning ended his second major league start. Beeler allowed four earned runs, six hits and walked four in five innings and did not record a strikeout.

Beeler (0-2) made his major league debut June 28 and allowed four hits and an earned run in a 3-0 loss to the Washington Nationals. He gave up four hits and struck out six.

Alcantara’s debut: Hot prospect Alcantara was 0-for-4 with two strikeouts in his first major league game. The 22-year-old infielder/outfielder, who hits from both sides of the plate, started at second base and hit in the No. 2 spot in the batting order Wednesday. The Cubs promoted him to take the spot of veteran Darwin Barney, who is on the paternity list.

Alcantara has hit .307 with 10 homers, 11 triples, 25 doubles and 62 runs in 89 games for Triple-A Iowa this season. He boasts an .890 OPS with 21 stolen bases in 24 attempts at Triple-A.

Renteria tossed: Cubs manager Rick Renteria was thrown out of the game in the bottom of the fifth inning by third-base umpire Andy Fletcher for arguing a foul-ball call. It was Renteria’s fifth ejection of the season.

Reds catcher Devin Mesoraco’s tapper down the third-base line with two outs, two on and three runs already in was just foul. Third baseman Luis Valbuena fielded the grounder and tagged third, but Fletcher called the ball foul.

The play was not reviewable.

Mesoraco grounded out to Valbuena moments later to end the inning.

Stat of the night: Simon (12-3) retired 13 straight Cubs after Rizzo’s game-tying home run in the third. Simon struck out eight in 6.2 innings, allowing four hits, two walks and one earned run.

What’s next: The Cubs wrap up the five-game series in Cincinnati at 11:35 a.m. CT, hoping to avoid a sweep. Kyle Hendricks will make his major league debut for Chicago, and Homer Bailey (8-5, 4.15 ERA) will take the hill for the Reds.

The Cubs return home for a three-game series leading into the All-Star break beginning Friday.