How it happened: Alejandro De Aza hit a two-run homer off Houston closer Jose Veras in the ninth, but the Sox came up short. The Astros jumped out to a quick lead in the second inning when Matt Dominguez smacked a bases-loaded double to left, scoring Chris Carter, Carlos Pena and Trevor Crowe. Carter had singled, but Pena and Crowe both reached on walks from Sox starter Hector Santiago. The Sox scored on a sacrifice fly from Alexei Ramirez in the sixth and an RBI single from Jeff Keppinger in the seventh. But the Astros answered in their half of the seventh, scoring two more on Jason Castro’s homer off Sox reliever Matt Thornton.
What it means: The White Sox dropped their fourth straight and have lost 12 of their last 13 on the road. They fell 10 games under .500. They need a win in Monday’s finale to avoid a four-game sweep.
Outside the box: Sunday’s loss was the first time anyone on the Sox roster had faced Houston starter Dallas Keuchel. Keuchel went 6 1/3 innings, giving up two runs on four hits.