Rapid Reaction: Tigers 8, White Sox 5

DETROIT -- Just one night after ending their seven-game losing streak to the Detroit Tigers, the Chicago White Sox were back to their same old losing ways against their AL Central rivals, dropping an 8-5 decision Wednesday night at Comerica Park.

How it happened: The Tigers scored all eight of their runs with two outs, scoring twice in the first, once in the second, twice in the third and then their final three times in the sixth. And after keeping Detroit's middle part of its order -- Torii Hunter, Miguel Cabrera, Prince Fielder and Victor Martinez -- in check in the series opener, that foursome combined for 11 hits, five RBIs and six runs in Wednesday's win. On Tuesday, they combined to drive in just two runs with four hits and scored two runs. The White Sox did have the tying run at the plate in the bottom of the ninth, but closer Joaquin Benoit got Alexei Ramirez to ground out to end the game. Chicago's Conor Gillaspie and Gordon Beckham each hit solo homers.

What it means: White Sox starting pitcher Dylan Axelrod has been accustomed to giving up the long ball all season, and Wednesday was no different. Axelrod gave up a two-run shot to Fielder in the first inning. He now has given up at least one home run in each of his last six starts and a team-high 18 for the season, including 11 in his last six starts.

Outside the box: Axelrod also continues to give up earned runs at an alarming rate. After giving up seven earned runs Wednesday, the White Sox's starter has now given up 29 earned runs over his past six starts. He also gave up 11 hits in 5 2/3 innings. It's the most hits he has given up in a game all season. His earned run average has ballooned to 5.33 since his start on June 5 when it was 3.73.

Off beat: Alex Rios is human after all. After tying an American League record with six hits in a nine-inning game Tuesday, the Tigers got Rios to ground out to shortstop in his first at-bat Wednesday. He followed that up with back-to-back strikeouts and then a groundout to second base to end his evening 0-for-4 at the plate.

Up next: Chicago wraps up its first three-game series of the season with Detroit by sending left-hander Chris Sale (5-8, 2.78 ERA) to the mound Thursday. The Tigers' scheduled starter is right-hander Anibal Sanchez (7-5, 2.70) in the 12:05 p.m. CST start time at Comerica Park.