How it happened: Pinch-hitter Chris Herrmann drove in Doug Bernier with the winning run in the ninth inning off Ramon Troncoso to continue the Twins' mastery of the Sox this season. Making his fourth career start, Andre Rienzo allowed one earned run -- a home run by Trevor Plouffe -- and left with a 3-2 lead after six innings. The Twins tied the game 3-3 in the eighth inning when Justin Morneau drove home Joe Mauer with an RBI single off Nate Jones. The Sox jumped out to an early lead on an RBI single by Adam Dunn and a sacrifice fly by Paul Konerko scored Gordon Beckham for a 2-0 lead.
What it means: The Sox's struggles against the Twins continue. After dropping three of four games last weekend at U.S. Cellular Field, the Sox lost the opening game of this four-game series to fall to 3-10 against Minnesota this season.
Outside the box: Beckham left in the fourth inning after suffering a quad strain and was replaced by Jeff Keppinger.