Rapid Reaction: Padres 4, White Sox 2

CHICAGO – The Chicago White Sox's 4-2 interleague defeat to the San Diego Padres on Saturday drops their record against National League West opponents to 2-6 this season.

How it happened: White Sox starter Andre Rienzo struggled with his command for the second consecutive outing and lasted just 3 1/3 innings, giving up three runs on seven hits with a walk. Dayan Viciedo had an RBI double in the fifth inning. The White Sox struck out 10 times Saturday against four Padres pitchers and now have 23 strikeouts during the first two games of the series.

What it means: The anticipation for Jose Abreu's return only grows as the White Sox find themselves scuffling at the plate. Abreu was hit by a pitch in a simulated game Saturday morning, but was good enough to continue the with one of his last two exercises before coming off the disabled list Monday. How good has Abreu been this year? Despite not playing for two weeks, he still entered Saturday’s game leading the team in home runs (15), RBIs (42) and OPS (.908).

Outside the box: It took 14 innings, but the White Sox finally used a hit to drive in a run during the current series when Viciedo doubled in the fifth inning. The White Sox scored their lone run Friday on a wild pitch and had a run in the second inning Saturday on Alejandro De Aza's double-play grounder.

Off beat: The home-plate collision has been eliminated this year, but a fender bender of sorts happened at home plate in the third inning. Adam Eaton threw out Carlos Quentin at home plate, with Quentin and catcher Tyler Flowers making solid contact on the play. The essence of the new rule is that players slide into home just like they would at any other base. Padres manager Bud Black appeared to argue that Flowers blocked the plate before the ball arrived, but the play was allowed to stand.

Up next: The White Sox will send left-hander Chirs Sale (4-0, 1.73 ERA) to the mound Sunday against San Diego in the finale of the three-game series. The Padres will counter with left-hander Erix Stults (2-5, 4.92) in the 1:10 p.m. start from U.S. Cellular Field.