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Rapid reaction: Twins 5, White Sox 4

MINNEAPOLIS -- The Chicago White Sox's six-game winning streak in Minnesota came to an end with a 5-4 loss to the Minnesota Twins on Wednesday.

How it happened: John Danks became the first White Sox starter to give up a run in the four-game series when he allowed five (four earned). The final, and deciding run came when Danks had Luke Hughes picked off first base. Paul Konerko’s throw to second went into left field and Hughes came all the way around to score. A frustrated Alex Rios struck out to leave the tying run at third in the eighth inning and snapped his bat over his knee.

What it means: The White Sox won three of four in Minnesota in three days but still lost a half game in the standings to the Tigers, who have kicked it into high gear. It was a nice turnaround after the brutal series in Detroit, but these last four games might have been more about the Twins shifting in to 2012 mode by playing their youngsters.

Outside the box: The White Sox ended up splitting the season series with the Twins at 9-9, which isn’t bad considering that Minnesota won the first six this year. A victory would have given the White Sox their first series victory over the Twins since 2005.

Up next: White Sox right-hander Gavin Floyd (12-10, 4.45 ERA) will pitch Thursday in the opener of three-game series against the Indians. Cleveland will counter with left-hander David Huff (2-3, 2.81) in the 7:10 p.m. start from U.S. Cellular Field.