Rapid Reaction: Indians 8, White Sox 4

CHICAGO -- Here's a quick look at the White Sox's 8-4 loss to the Cleveland Indians on Friday:

How it happened: Lonnie Chisenhall got the best of Mark Buehrle, hitting a pair of two-run homers against the White Sox veteran lefty. The Sox offense was able to come back from the first blast as they tied the game 2-2 in the third inning. However, Chisenhall's second homer began the scoring in a five-run sixth for the Indians, a deficit that proved too difficult to overcome.

What it means: With Buehrle headed for free agency after the season, his days in a White Sox uniform may be numbered. Though he's having possibly his best season since 2005, his last two starts (combined 9 innings, 18 hits, 14 earned runs) have been less than impressive. Buehrle should have at least one more start in front of the home crowd to ensure that if this his last year on the South Side, he can at least leave the fans with a positive memory upon his departure.

Outside the box: Rookie reliever Addison Reed made his second appearance and showed why many believe he could be a closer in the future. In his one inning of work, Reed worked around a double and struck out three. Reed fanned 111 and walked only 14 at four levels in the White Sox minor league system this season.

What’s next: After a strong performance in his first start since returning from the disabled list, Philip Humber (9-8, 3.45) looks to build on that outing. He faces Fausto Carmona (6-14, 5.18) as the White Sox continue their four-game series against the Indians at 3:10 p.m. Saturday at U.S. Cellular Field.