1. Harvard won an NCAA tournament game for the first time in program history. The Crimson defeated No. 3-seed New Mexico. Harvard is the first 14-seed or lower from the Ivy League to win an NCAA tournament game.
2. Since seeding began in 1979, the 46-point victory by 5-seed Virginia Commonwealth over No. 12 Akron was the largest margin of victory ever by any team seeded lower than 2. That record lasted for about an hour. Syracuse, a 4-seed, broke it with a 47-point win over Montana.
3. Southern's six-point loss against Gonzaga was the closest by a No. 16 seed against a No. 1 seed since 1996, when Western Carolina lost by two against Purdue. Southern is only the fifth No. 16 seed in the past 20 years to come within single digits of a 1-seed.
4. Vander Blue's go-ahead layup with one second remaining against Davidson was the first game-tying or go-ahead shot made in the final 10 seconds of a game in the past two NCAA tournaments. Prior to Blue's shot, players missed the previous 22 attempts in those situations, dating back to the 2011 NCAA tournament.
5. With Butler's win over Bucknell, Brad Stevens is now 12-4 in the NCAA tournament. Stevens is the seventh coach to win at least 12 of his first 16 NCAA tournament games, according to the Elias Sports Bureau. The only coaches with a better record in their first 16 NCAA tournament games are Tom Izzo and Steve Fisher.
6. Russ Smith had eight steals for Louisville in its win over North Carolina A&T, matching the most in any NCAA tournament game (steals became official in 1986). The last player with eight steals in a game was North Carolina's Ty Lawson in the 2009 national championship game.
7. With its loss to No. 12-seed California, UNLV, a No. 5 seed, became the third team ever to lose four consecutive games in the round of 64 as the higher seed, joining Clemson (1998-2010) and BYU (1995-2009).