Mercer pulled off the first huge bracket buster of the tournament by knocking out Duke on Friday.
Just 3.3 percent of the 11 million Tournament Challenge brackets had the Bears winning, by far the least popular of the 14-seeds to advance.
Conversely, 20.9 percent of brackets had Duke in the Final Four and 5.3 percent had the Blue Devils winning it all, the seventh-most-popular choice overall.
There are now 2,185 perfect brackets (out of 11 million) in Tournament Challenge. Heading into the game, there were 18,741 perfect brackets.