The Mavs are not certain about the severity of the injury to Ellis, who has played in 237 consecutive games, a streak that dates to the 2012-13 season opener.
“It’s very sore, but we don’t know the extent of it,” coach Rick Carlisle said. “We’ll see how he feels in the morning and go from there.”
Ellis, the Mavs' leading scorer with 19.3 points per game, did not speak to reporters before leaving the AT&T Center on crutches.
Ellis injured the calf when he was inadvertently kneed while defending Spurs sixth man Manu Ginobili during the third quarter. Ellis limped off the court with 6:43 remaining in the third quarter and initially received treatment on his right knee, as pain was shooting through his leg.
Ellis, the Mavs’ leading scorer who has not missed a game since the 2011-12 season finale, played hurt for week after he strained his left hip two games before the All-Star break. Ellis said after scoring a season-high-tying 38 points in Tuesday's home win over the Spurs that he finally felt healthy again.
Ellis has played through multiple injuries during his two-year tenure in Dallas, but owner Mark Cuban said the decision on his status for Sunday's game in Indiana would be determined by the Mavs' medical staff.
"Our trainers will evaluate the situation and communicate with him," Carlisle said. "I don't see us putting him out there if he doesn't feel good. You can't underestimate his ability to bounce back from things. He's a fighter, he loves to compete and he hates missing game. That said, we aren't going to put him in harm's way."