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Lineups: Jake Peavy scratched from start

ARLINGTON, Texas -- Jake Peavy has been scratched for Thursday night's start against the Rangers because of back spasms, so the Rangers will see left-hander Hector Santiago instead.

It means the Rangers will face a left-handed starter for the third straight game. How this will impact the Rangers' lineup remains to be seen. David Murphy is supposed to start Thursday, but he has sat the last two nights with a left-handed starter going for the White Sox. It's also currently 46 degrees, which means the cold weather could impact designated hitter Lance Berkman and his sore knee and maybe catcher A.J. Pierzynski and his sore oblique (which he said was much improved after a pinch-hit appearance in Wednesday's game).

Santiago, a 23-year-old from Newark, N.J., is 0-1 with a 2.51 ERA in seven appearances. He will be making his first start of the season and fifth of his career. He appeared twice against the Rangers in 2012 and allowed a hit and no runs in two innings. Ian Kinsler had the lone hit out of seven Rangers' at-bats.

The 31-year-old Peavy is 3-1 with a 3.38 ERA for the season. He won his most recent start last Friday against Tampa Bay. But the two-time All-Star hasn't had great success against the Rangers, so Peavy being scratched might not be that big of a break.

Here are the lineups for Thursday's game:

RANGERS

2B Ian Kinsler

SS Elvis Andrus

DH Lance Berkman

3B Adrian Beltre

RF Nelson Cruz

C A.J. Pierzynski

LF Jeff Baker

1B Mitch Moreland

CF Craig Gentry

SP Justin Grimm

WHITE SOX

LF Alejandro De Aza

2B Jeff Keppinger

RF Alex Rios

1B Adam Dunn

DH Paul Konerko

3B Conor Gillaspie

SS Alexei Ramirez

C Tyler Flowers

CF Dewayne Wise

SP Hector Santiago