The San Diego Padres will send Odrisamer Despaigne (3-4, 4.38 ERA) to the mound to face Jesse Chavez (2-6, 2.64 ERA) and the Oakland Athletics on Wednesday night for the first of a two-game series at O.co Coliseum.
Despaigne has struggled away from Petco Park this season with a 5.25 ERA on the road compared with 3.82 at home. Batters have hit .303 against him on the road compared with .243 at home. Over his last three road starts, he is 0-2 with a 6.35 ERA and 1.47 WHIP.
Wil Myers is hitting .326/.396/.605 in his last 10 road games, with four doubles, one triple, one home run and five RBIs. His 1.000 road OPS over that stretch is 11th in the National League.