Missouri leads Miami (Ohio) 7-0 early in the third quarter, but the Tigers will have to go the rest of the way without senior linebacker Will Ebner.
Ebner is one of the defense's hardest hitters, but an ankle injury will keep him from returning.
He played last year through pain and a foot injury that required postseason surgery. He also missed two games with a neck strain.
Ebner started the game, but was listed as a co-starter at middle linebacker with fellow senior Luke Lambert.
For now, it looks like Lambert will have to carry the middle of the Tigers' defense.