ACC viewer's guide: Week 6

Conference play all around! Let's take a quick look at what's on the docket.

Virginia Tech (3-2, 0-1) at North Carolina (2-2, 0-1), 12:30 p.m., ESPN3. Line: Virginia Tech by 3. #VTvsUNC. The biggest storyline discussed in the run-up to this game focused on the propensity for both secondaries to give up big plays. But keep an eye on the Virginia Tech run game. Unlike East Carolina and Clemson, Virginia Tech will work hard to try to establish the run. But how will the overall unit look with Shai McKenzie out for the season? Coach Frank Beamer said the staff has not come up with a set rotation yet, but somebody else will have to step up to complement leading rusher Marshawn Williams.

NC State (4-1, 0-1) at Clemson (2-2, 1-1), 3:30 p.m., ESPNU. Line: Clemson by 15. #NCSTvsCLEM. Quarterbacks take center stage in this meeting as NC State's Jacoby Brissett and Clemson's Deshaun Watson have emerged as two of the best signal-callers in the league. Brissett has thrown 13 touchdown passes to one interception; Watson has thrown 10 touchdown passes to one interception. Watson leads the nation in yards per pass attempt (11.9) and is second in the nation in pass efficiency; Brissett has thrown 156 passes without an interception. Both teams appear to be in good hands at the position for the foreseeable future.

Wake Forest (2-3, 0-1) at No. 1 Florida State (4-0, 2-0), 3:30 p.m., ABC. Line: Florida State by 38. #WAKEvsFSU. Will this be the first FBS game all season in which Florida State coasts? The Noles have needed comebacks to win their past two games, but Wake Forest should not present an upset threat. However, Wake Forest has been impressive on defense -- especially Tylor Harris, whose three fumble recoveries last week against Louisville are the most for any player in one game since the NCAA started keeping stats at the turn of the century. Where the Deacs will be totally overwhelmed is on offense. John Wolford already has 10 interceptions, and Wake has given up 25 sacks.

Miami (3-2, 1-1) at Georgia Tech (4-0, 1-0), 7:30 p.m., ESPN2. Line: Georgia Tech by 2. #MIAvsGT. This is a big-time prove-it game for the Jackets, who had a bye to prepare for the Hurricanes after beating Virginia Tech a few weeks ago. Georgia Tech has not dominated anybody but has found ways to win. However, Duke Johnson may be too much for this Jackets defense to handle. Last year, Johnson had 184 yards against Georgia Tech. The Jackets rank last in the ACC in rush defense. Miami has handled the triple option well in five straight wins, but its defense can't simply rest on its performance against Duke last week. Miami also has to prove it can be consistent on that side of the ball.

Pitt (3-2, 1-0) at Virginia (3-2, 1-0), 7:30 p.m., ESPN3. Line: Virginia by 6. #PITTvsUVA. Virginia quarterback Greyson Lambert will be a game-time decision, though he is listed as questionable on the team's injury report. No matter who plays quarterback, the focus will be on the Virginia run defense against James Conner, who failed to reach 100 yards for the first time all season last week against Akron. The Hoos provide a bigger test, ranking No. 10 nationally against the run. If Virginia wins, the Hoos would be 2-0 in ACC play for the first time since 2009.