Armstead (knee) and Strief (elbow) did not practice during this short week following a Monday night game. But both players have played through those injuries in recent weeks.
Quarterback Drew Brees (foot) is also listed as questionable, but he was able to practice on a limited basis Friday and insisted that he plans to play.
Receiver Marques Colston (chest) and tight end Benjamin Watson (knee) are also questionable after not practicing all week. The NFL Network's Rand Getlin reported that Colston will not play Sunday vs. the Jacksonville Jaguars.
The game is scheduled for 4:05 p.m. ET in the Mercedes-Benz Superdome.