But Rolle won't exchange pleasantries with his former teammates once the game starts.
"It is going to be good to see those guys and play against them," Rolle said in his weekly spot on WFAN radio. "We are all great friends off the field. On the field ... if that means bring the noise, then so be it, we are definitely going to bring the noise.
"We will hug and shake hands after the game," Rolle continued. "But during that game time, there won't be any patting on the butt."
Rolle has remained close to Jacobs, but he said on Monday he will attack Jacobs -- if Jacobs finally makes his 49ers debut -- the same way he attacks any other running back.
Lingering pain: Rolle said his bruised knee is feeling better, but he admits it is "going to take some time" to get back to full strength.
Rolle banged his left knee hard against a television camera on the sideline of the end zone in Carolina on Nov. 20.
He has not missed any games and will play Sunday, but the knee issue continues to bother him a bit.
"Definitely better than I was a few weeks ago," Rolle said. "It is a battle, a constant battle each and every day. I just try to do whatever I can to go out there and perform on Sundays.
"With the knee injury, it is going to take some time," Rolle added. "Actually, I never thought it would be this crucial. It is a little lingering process. Not anything too serious but you know something that just lingers around and sticks with you a little bit. But I will be fine."
Another loss: The Giants are already without Kenny Phillips (knee). Now they are without Will Hill, who was suspended for the next four games for violating the NFL's performance enhancing substances policy by taking Adderall.
"It is difficult," Rolle said of losing Hill. "I can't sit here and lie and say it is not difficult. It is difficult. Especially because Will Hill has been playing good football for us."
The Giants will have Tyler Sash back. Sash took Hill's roster spot after serving his own four-game suspension for taking Adderall.
"Unfortunately we had Kenny going down and I'm still dealing with this injury," Rolle said. "It just seems like if it is not one thing, it is another. We are a tough, close unit. We are going to make sure Will will stay level-headed and make sure he keeps his head into the game. And at the same time we will get (Sash) up to speed."