Running back Ahmad Bradshaw and wide receiver Hakeem Nicks were among seven New York Giants who did not practice.
They were joined by center David Baas, cornerback Corey Webster, cornerback Will Blackmon, linebacker Jacquian Williams and linebacker Chase Blackburn.
Barring a setback, these Giants expect to play against New England in the Super Bowl.
"Trying to be smart, not aggravate something that is there that we'll be able to manage in a short amount of time provided there isn't anything else that happens," head coach Tom Coughlin said.
Jonathan Tisch, co-owner and treasurer of the team, was on crutches with a cast on his foot in the area where the injured Giants were at the start of practice.
Bradshaw sits out the first couple of practices as part of his routine with his foot injury. He'll have two weeks between games to rest his foot for the Super Bowl. Nicks has a shoulder injury he suffered during the NFC Championship Game although Coughlin said the wideout will be fine since he did return and finish the game in San Francisco.
"I'm not [concerned]," Nicks said. "This is what you play for. Whether it's hurting or not I'm going to go regardless. Right now I'm just taking these little bit of days we got to get it ready."
Baas suffered an abdomen injury during the win against the Niners but returned and played as well. He also is listed with a neck ailment. The center did have a neck injury earlier this season. Blackburn was listed with a calf injury. Both told reporters in the locker room that they expect to practice on Friday.
Webster has been dealing with a hamstring injury for the past few weeks but has not missed any games. Blackmon is listed with a knee injury. Aaron Ross briefly replaced him on a punt return against San Francisco.
Safety Tyler Sash has been cleared from tests for a concussion and went through a full practice. Williams is new to the injury report with a foot injury.
Defensive end Osi Umenyiora (ankle/knee) was limited in practice as part of his routine.