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Rapid Reaction: Braves 6, Mets 3

NEW YORK -- Time to panic ... maybe just a little?

After opening the game on the bench with wrist discomfort, Mets nemesis Freddie Freeman ultimately produced five RBIs. The damage included a tiebreaking three-run homer in the ninth inning against Jeurys Familia as the Atlanta Braves beat the New York Mets 6-3 on Wednesday at Citi Field.

Familia had allowed one run over his previous 25 innings. His 0.36 ERA since July 31 had been the lowest in the majors during that span (minimum 20 innings).

The Mets lost consecutive rubber games to the Miami Marlins, New York Yankees and Braves and went 3-6 on their homestand.

The Amazin's (85-67) magic number dropped to 5 and their lead atop the National League East remained at 6½ games thanks to the Washington Nationals’ loss to Baltimore Orioles.

With consecutive losses to the Braves, the Mets finished the season series with an 11-8 record against Atlanta. That matches the most wins in Mets history in a single season against the Milwaukee/Atlanta franchise. The Mets went 11-7 against the Braves in 2006.

Freeman had delivered a two-run double in the seventh against Addison Reed that had staked the Braves to a 3-2 lead.

David Wright answered a half-inning later with a two-out RBI single against Brandon Cunniff to even the score. Wright appeared to bark a profanity at Freeman upon reaching first base.

Seventh swoon: Bartolo Colon retired the first 14 batters he faced and seemed destined to match Pedro Martinez for the second-most wins in MLB history by a Dominican-born pitcher. Then things quickly unraveled in the seventh inning.

Colon allowed three singles in a four-batter span to open the frame. Reed then entered and allowed all three inherited runners to score as the Braves took a 3-2 lead.

Colon had been perfect until Jace Peterson slapped a two-out infield single to shortstop in the fifth.

In the seventh, Michael Bourn greeted Reed with an RBI single. Freeman followed with a pinch-hit, two-run double as the Braves took the lead.

Although he has now tossed 12 2/3 scoreless innings since arriving in a trade with the Arizona Diamondbacks, Reed has now allowed all five inherited baserunners to score.

Until the meltdown, Colon had been in position to achieve a pair of notable distinctions. A win would have given him 219 career victories, which would match the ex-Met Martinez for the second-most by a Dominican-born pitcher in major league history. Only Juan Marichal (243) has produced more wins. Colon also was bidding to secure his second straight 15-win season. He would have become the first Mets pitcher with 30 wins over a two-season span since Al Leiter in 1998 (17) and 1999 (13).

Odds & ends: After getting a day off, Travis d'Arnaud returned to the starting lineup Wednesday and snapped an 0-for-18 skid with second-inning single. … Daniel Murphy staked the Mets to the early lead with a first-inning solo homer against Williams Perez. Murphy's 13th long ball of the season matched his career high. … Tyler Clippard plunked leadoff batter Pedro Ciriaco on the left side in the eighth, but Clippard ended up tossing a scoreless frame. He had allowed nine earned runs and four homers in his previous 8 2/3 innings. … Juan Uribe had a pinch-hit single in the ninth in his first action since suffering a chest bruise.

What's next: Steven Matz (4-0, 1.80 ERA) opposes right-hander Josh Smith (0-2, 7.71) as the Mets open a four-game series in Cincinnati on Thursday at 7:10 p.m. ET.