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NFC West: Injury situations that matter

Arizona: A concussion continues to sideline veteran quarterback Derek Anderson. The team hasn't committed to him as its starter even if healthy enough to start. John Skelton figures to play one way or another. I have a hard time believing the Cardinals would send the newly signed Richard Bartel onto the field after one week of practices, but it wouldn't be the first time someone misread the quarterback situation in Arizona. On defense, Darnell Dockett (shoulder) and Greg Toler (foot) participated fully in practice Wedneday. Dockett looked healthier against St. Louis, a big boost for Arizona on defense. Receiver Steve Breaston (knee) was among six players limited Wednesday.

St. Louis: The Rams have generally done a good job working through manpower issues in their secondary, but the situation appears unfavorable heading into a game against Drew Brees and New Orleans. Free safety Oshiomogho Atogwe (shoulder) and cornerback Ron Bartell (neck) did not practice Wednesday. Safety Craig Dahl (knee), cornerback Justin King (shoulder) and cornerback Jerome Murphy (hamstring) were limited. Meanwhile, coach Steve Spagnuolo said quarterback Sam Bradford's sore ankle was no longer an issue. Bradford did not appear on the injury report. An ankle injury continues to sideline tight end Mike Hoomanwanui. His absence hurts.

San Francisco: The 49ers remain without left tackle Joe Staley and kicker Joe Nedney. Neither will play Sunday in the team's second full game since Pro Bowl running back Frank Gore landed on injured reserve with a fractured hip. Gore's primary replacement, Brian Westbrook, is getting extra rest as the team tries to keep his 31-year-old legs fresh. Nose tackle Aubrayo Franklin (groin), linebacker Takeo Spikes (ankle) and tight end Delanie Walker did not practice Wednesday. Walker missed part of the Green Bay game last week after suffering the injury, but he was able to return. Gore's absence and quarterback Alex Smith's return to the lineup could facilitate more pass-oriented personnel groups. The 49ers will still want to test the Seahawks' run defense.

Seattle: Nose tackle Colin Cole and tight end John Carlson participated fully in practice Wednesday. An ankle injury has sidelined Cole for the Seahawks' last five games. The team needs his presence against the run. Carlson's value has leveled off a bit now that tight end Cameron Morrah is becoming a factor in the receiving game and fullback Michael Robinson is available. Carlson had taken some of the fullback reps when Robinson was out. Seattle remains cautiously optimistic that top receiver Mike Williams will play against the 49ers despite ankle and foot injuries. Williams did not practice Wednesday. Neither did guard Chester Pitts (ankle), receiver Ben Obomanu (hand), defensive end Chris Clemons (ankle), middle linebacker Lofa Tatupu (knee) or linebacker Mike McCoy (head). Tatupu's injury is limiting him. He limps following some plays and lacks his usual explosiveness. Watching him play against Carolina, I wondered if how many more games he would last.