Sando's best guesses: Week 2 predictions

The NFC West surprised us (translation: me) in Week 1 with San Francisco dominating at Green Bay, Kevin Kolb leading a fourth-quarter comeback for Arizona and St. Louis nearly shocking Detroit at Ford Field.

I've got a 1-2 record in predictions to show for opening week. A clock operator's error in Detroit might have been all that stood between me and 0-3.

Let's give this another try with a look at Week 2:

  • Arizona Cardinals at New England Patriots, 1 p.m. ET. Cardinals defensive coordinator Ray Horton relishes "chess matches" with opposing coordinators. He'll get a shot at NFC West alum Josh McDaniels, who is now running the Patriots offense. The board appears stacked in McDaniels' favor, but there's also no pressure on the Cardinals. They're double-digit underdogs with a 1-0 record and a capable defense. Sando's best guess: Patriots 24, Cardinals 13.

  • Washington Redskins at St. Louis Rams, 4:05 ET. The Rams' defensive staff should benefit from having seen how the Redskins planned to use Robert Griffin III this season. I'll go out on a limb and say the Rams, armed with a smart defensive plan and opportunistic cornerbacks, find a way to win their home opener under Jeff Fisher. Sando's best guess: Rams 20, Redskins 17

  • Dallas Cowboys at Seattle Seahawks, 4:05 ET. Last week, I let the Cardinals' problems on the offensive line talk me out of picking them to win a home game. Wrong call. This week, the Seahawks' line problems are tempting me to make a similar decision. Not this time. The matchups favor Dallas, but Seattle needs to win this one at home. Sando's best guess: Seahawks 20, Cowboys 19

  • Detroit Lions at San Francisco 49ers, 8:20 ET. The 49ers have to like this matchup. They won't have to worry too much about the Lions' ground game, an advantage for their defense. San Francisco's offense has gone six-plus games without committing a turnover. That streak won't continue forever, but it's not a fluke, either. I trust the 49ers more than I trust the Lions when it comes to protecting the football. Sando's best guess: 49ers 27, Lions 17.

Thanks for coming along. Note that we've also got the "You called it" competition going, plus the Pigskin Picks group.

Now, where am I wrong on Week 2? Please keep answers under 1,000 words.