NFL Live: Highlighting Week 15 matchups

Mark Schlereth and Tedy Bruschi are pointing to the San Francisco 49ers' game against New England as the NFL's best matchup in Week 15.

They offer thoughts on that game and a few others in the video above.

49ers-Patriots is the only game involving an NFC West member that features two teams with winning records. The game between St. Louis (6-6-1) and Minnesota (7-6) just misses the cut. Week 15 has six total NFL games featuring two teams with winning records.

Seattle faces a Buffalo team that has yet to defeat an opponent with a winning record. The Bills are 5-8 with victories over Kansas City, Cleveland, Arizona, Miami and Jacksonville. Buffalo's strength of victory is .277, tied with San Diego for lowest in the NFL this season.

Meanwhile, Arizona and Week 15 opponent Detroit are riding a combined 14-game losing streak, nine for the Cardinals and five for the Lions. Detroit can finish the season 3-1 against the NFC West with a victory in that game.