Rapid Reaction: Giants 29, 49ers 17

Posted by ESPN.com's Mike Sando

The 49ers can keep talking about close defeats and not getting blown out, but at some point the team needs to win a game.

It wasn't going to happen against the Giants at the Meadowlands.

Quarterback J.T. O'Sullivan tossed two more interceptions. Yes, one was on a pass delivered as the first half ended.

But he lost a fumble for a safety late in the game, and the 49ers struggled again on third down. Frank Gore never got going on the ground.

The 49ers should bounce back at home against the Seahawks in Week 8, but there are no guarantees with O'Sullivan turning over the football. A loss to Seattle would mark five defeats in a row, a tough way for coach Mike Nolan to head into the bye week.