Arians said it's the same left hamstring Fitzgerald tweaked Sept. 11, but the injury is in a different spot.
"We'll wait and see by game time," Arians said.
Fitzgerald was limited Wednesday and Thursday but practiced in full Friday. After seeing how the hamstring hampered him during the Lions game, Fitzgerald will be cautious Sunday.
This is just the latest setback for Fitzgerald, who has 24 receptions. That's fewest through the first five games of a season since 2004, his rookie year, when he had 22, according to ESPN Stats & Information.
Fitzgerald hasn't lived him to his Hall of Fame standards in his last 21 games. He has just two games with at least 100 receiving yards during that span and has a total of 1,086 yards, far less than the 1,411 yards he had in 2011.
Other injury news"
Rookie LB Kenny Demens (hamstring) was also listed as questionable.
Listed as probable were LB John Abraham (shoulder), LB Jasper Brinkley (groin), G Daryn Colledge (shin), DT Darnell Dockett (groin), S Rashad Johnson (finger), LB Kevin Minter (hamstring), DE Ronald Talley (wrist), LB Daryl Washington (knee).