What it means: The Titans blew a chance to get back to leading the pack for the sixth seed in the AFC and couldn’t close to within a game of the Colts in the AFC South. They are now 5-7. Ryan Fitzpatrick threw three interceptions and lost a fumble. Kicker Adam Vinatieri made up for the Colts' inability to find the end zone until the end, when they drove 92 yards in 11 plays over 6:12, capped by a 4-yard Donald Brown touchdown that provided the final margin.
Stock watch: Tight end Taylor Thompson was called on for a major role with Craig Stevens inactive because of a concussion and Delanie Walker lost in the first half to a concussion of his own. Thompson looked thoroughly overmatched, booting a couple of catchable balls and hardly providing a reliable option for Fitzpatrick.
Four in a row: The Titans have played reasonably well in four games against the Colts since Chuck Pagano took over as coach and Andrew Luck took over as quarterback. But Tennessee is 0-4 in those games as the Colts have found a way every time in the second half.
Giant goat: Well away from the tackle at the very end of the first half, linebacker Moise Fokou shoved fullback Stanley Havili in the back and drew a personal foul penalty. The 15 yards put the Colts in range for a 37-yard Vinatieri field goal.
What’s next: The Titans travel to Denver for a matchup with Peyton Manning and the Broncos.