Rapid Reaction: Giants 29, 49ers 17

Posted by ESPN.com's Matt Mosley

The Giants looked sloppy on offense for the second consecutive game, but the defense bailed them out this week.

Replacing Antonio Pierce at linebacker, Chase Blackburn had the best game of his four-year career. He had 10 tackles, a sack and a forced fumble in Sunday's 29-17 win.

On Monday night, the Browns muted the Giants' pass rush, but 49ers quarterback J.T. O'Sullivan was under siege from the start. Defensive end Justin Tuck had two sacks and two forced fumbles.

The Giants won the turnover battle, and that was the difference. Tom Coughlin will be upset about a special teams breakdown on a blocked field goal attempt that was returned for a touchdown in the second half.

But it was the defense's ability to eliminate Pro Bowl running back Frank Gore that made the 49ers one-dimensional.

Eli Manning was 16-of-31 for 161 yards and a touchdown. He never got in a rhythm, but he didn't make the back-breaking mistakes that occurred against the Browns.

Giants running back Brandon Jacobs was held to 69 yards, but he found the end zone twice.

And for the first time this season, the Giants gave Ahmad Bradshaw some meaningful carries. New York continues to get the most of its running backs. Derrick Ward had three catches for 50 yards.

Giants safety Michael Johnson had the first two interceptions of his career. O'Sullivan was running for his life most of the game, and four different defensive linemen had sacks for the Giants.