Woodley, who injured his hamstring in Sunday's win over New England, will not play against Baltimore and likely will miss the next game at Cincinnati, according to the Post-Gazette. He leads the AFC with nine sacks.
The losses of Woodley and Harrison are major blows to the Pittsburgh pass rush. Woodley and Harrison have totaled 82.5 sacks since 2008, accounting for half of the Steelers' sacks over that time. Both are expected to return after the Nov. 20 bye.
This run of injuries will test Pittsburgh's young depth at linebacker. The Steelers will lean on Lawrence Timmons, who doesn't have a sack this season, along with rookie fifth-round pick Chris Carter and Stevenson Sylvester, both of whom have yet to record sack in the NFL.
Woodley had expected to play against Baltimore on Sunday night. "I'll be in there," Woodley told The Pittsburgh Tribune-Review two days ago. "I have a week [to heal]."