This would be a good example of musical chairs if Jackson can pull it off. He suffered a knee injury in Week 1 against the New York Jets and Spiller took over. Now, Spiller has a shoulder injury and Jackson is healing faster than expected. Jackson says he's about 70-75 percent sure he can play against the Patriots.
Sunday's game at Ralph Wilson Stadium will have huge AFC East implications. The Bills (2-1) have a chance not only to improve to 3-1 but also put the Patriots in a 1-3 hole. A loss would put both teams even at .500.
If Jackson can get healthy and quickly return to his 2011 form, the Bills have a chance to beat New England at home for the second straight year.