That's not good news for an 0-2 team that will face quarterback Eli Manning and the league's top passing game.
Team officials said on Friday that Thomas was not cleared by doctors after suffering a concussion in Sunday's 24-23 loss at Buffalo. Thomas practiced on Thursday and Friday and, according to coach Ron Rivera, passed all the necessary team tests.
But as Thomas wrote on Twitter:
I will not be playing this NYGiants game for precautionary reasons (doctor). Still put together a week of great team practice.
— Josh Thomas (@Josh_Thomas22) September 20, 2013
Edwards missed his third straight day of practice on Friday with a thigh injury.
"Not looking good," said Rivera, adding a decision on Edwards' status will be made on Saturday.
Rivera left it open that either veteran Drayton Florence or Josh Norman would start on the left side for Thomas. Florence was signed on Wednesday night after being among the final cuts in the preseason.
Norman has been fighting through a deep thigh bruise and sprained knee.