Davis, Reid on pace to play

SANTA CLARA, Calif. -- A final decision will likely be made Sunday, but it appears the San Francisco 49ers will have star tight end Vernon Davis and standout rookie safety Eric Reid on Sunday in New Orleans.

Both players had to leave last week’s game against Carolina with concussions. But they are symptom-free, and barring a setback will play Sunday. They had a contact test Friday.

Both will be greatly needed. Davis has made the 49ers’ offense go this season, and Reid will be needed against the pass-happy Saints.

The 49ers will, though, be without defensive tackle Ryan McDonald. He’s been ruled out with a high ankle injury. It’s been expected he’d miss the game all week. Tony Jerod-Eddie -- who has played well this season -- will start for McDonald.

Receiver Mario Manningham is listed as questionable with a knee injury. He was limited in practice all week, but offensive coordinator Greg Roman said Thursday that Manningham is fine. He made his season debut last week. He had been out since December with a knee injury.

Fellow receiver Michael Crabtree practiced Friday after not practicing the past two days. But he did a lot of work both days, coach Jim Harbaugh said. Crabtree is on pace to be activated to the 53-man roster by Nov. 26. He suffered a torn Achilles in May.

Harbaugh said running back Marcus Lattimore will begin practicing next week. He is not expected to play until next season. Lattimore is a fourth-round pick who suffered a major knee injury at South Carolina last fall.

Tight end Garrett Celek is doubtful with a hamstring injury. The 49ers have an open roster spot. There is a good chance they promote tight end Derek Carrier from the practice squad Saturday. If so, it wouldn’t a be shock if Carrier is active, because the 49ers will want three tight ends.