What it means: After a string of highly competitive games, the Bills suffered one of the their worst losses. The Vikings rolled even with quarterback Brett Favre, receivers Percy Harvin and Greg Lewis and right guard Steve Hutchinson sidelined. The Bills are 2-10.
Hero: Adrian Peterson thrived against the NFL's worst defense. Bills rookie linebacker Arthur Moats knocked Favre out of the game on the third play, but the Vikings didn't need him. Peterson rushed 16 times for 107 yards and three touchdowns.
Goat: Bills cornerback and kick returner Leodis McKelvin had a rough afternoon. Vikings receiver Sidney Rice made a scintillating play to outjockey McKelvin and come down with a 31-yard touchdown catch in the first quarter. McKelvin fumbled the ensuing kickoff, helping the Vikings score 28 points in a 5:45 stretch.
Streak extended: Bills quarterback Ryan Fitzpatrick needed almost 56 minutes to lengthen his streak to 13 games with a touchdown pass, finding David Nelson for a 12-yarder with the game out of hand. Fitzpatrick also fumbled twice, losing one.
Defensive highlights: Buffalo's defense had its moments despite the lopsided score. Cornerback Drayton Florence had his first multi-interception game and his first interception return for a touchdown. Donte Whitner and McKelvin picked one apiece.
What's next: The Bills and Cleveland Browns have played some awful games in recent years. Remember that 6-3 gem last year? Next week's meeting should be livelier, with Trent Edwards and Derek Anderson long gone. The Browns defeated the Miami Dolphins 13-10 in Sun Life Stadium.