Rivers practiced on a limited basis Wednesday and Thursday before sitting out Friday's practice. He was listed as doubtful on the injury report.
In addition to Rivers, the Bills will be without rookie linebacker Randell Johnson. The Bills are expected to start Brandon Spikes, Nigel Bradham and rookie Preston Brown at linebacker, with Ty Powell and Larry Dean as the reserves.
Here is the full list of Bills inactives:
RB Bryce Brown
TE Chris Gragg
LB Keith Rivers
LB Randell Johnson