Canucks lead series 1-0
Roberto Luongo stopped all 20 Nashville shots for his third career playoff shutout.
The host Canucks won their sixth straight Game 1 of a playoff series.
Pekka Rinne stopped 29 of 30 shots in a losing cause for the Predators, who are in the Conference Semifinals for the first time in their history.
Chris Higgins' second goal of the playoffs 12:14 into the second period was the only goal of the game.
Nashville is now 3-14 in road playoff games all-time.
Game 2 of the series is Saturday in Vancouver at 9 p.m. ET.