Locker, with the press box full of NFL scouts, completed just 7 of 14 passes for 64 yards with two interceptions in a 41-0 loss.
Stanford's Andrew Luck didn't exactly put up huge numbers. He completed 19-of-26 for 192 yards with a TD and an interception. He also ran for a 51-yard TD.
But the QBs weren't the difference. The difference was Stanford rushing for 278 yards, while the Huskies had 107.
Stanford (7-1, 4-1) made a big statement and should move into the top-10 before it plays host to Arizona on Saturday in a marquee showdown between once-beaten teams.
The Huskies, shut out at home for the first time since 1976, fall to 3-5 overall and 2-3 in the Pac-10. UCLA's visit next weekend becomes a must-win for bowl hopes.