Stanford has lost the Andrew Luck of its defense.
Linebacker Shayne Skov, the Cardinal's leading tackler and emotional leader, is out for the season with a left knee injury, the school announced Monday.
Skov hurt the knee in the second quarter of the Cardinal's 37-10 victory over Arizona.
The 6-foot-3, 251-pound redshirt junior was replaced by Jarek Lancaster. Sophomore Blake Lueders and redshirt freshman AJ Tarpley also are options, and it's likely that Skov's loss also will mean more playing time for touted true freshman James Vaughters.
Stanford is off this week. It plays host to UCLA on Oct. 1.