Moore, who missed the Pittsburgh Steelers' first two games because of a nagging groin injury, has practiced both days this week.
The ninth-year veteran will make his Steelers debut against the 2-0 Panthers barring a setback.
McLendon, who left the Steelers’ 26-6 loss to the Ravens last Thursday with a shoulder injury, also should play in Carolina unless he experiences a setback.
Rookie running back Dri Archer (ankle) and left guard Ramon Foster (ankle) were limited in practice. Archer did not play against the Ravens because of a sprained ankle.
Steelers coach Mike Tomlin did not mention Foster when he gave an injury update Tuesday at his weekly news conference.
A number of Panthers players didn’t practice on Wednesday, including linebacker Thomas Davis (hip), defensive tackle Dwan Edwards (back), running back DeAngelo Williams (thigh) and wide receiver Kelvin Benjamin (knee).
Defensive end Greg Hardy did not practice and the Panthers are expected to take Hardy off the 53-man roster and place him on the NFL’s exempt list following a bench conviction for assaulting his former girlfriend.