UMass at Vanderbilt, FSN
When these teams met last season in Foxborough, Massachusetts, it was a competitive game before a Vandy team that would win nine games locked down a 24-7 victory. UMass gave Colorado a scare before falling 41-38 last weekend, so reeling Vandy had better come to play or it might be on upset alert.
Central Florida at No. 20 Missouri, SEC Network
When last we saw UCF, the Knights were suffering a heartbreaking 26-24 loss to Penn State in their season-opening matchup in Ireland. Mizzou is a 10-point favorite over the Knights, who won the Fiesta Bowl last season before stars Blake Bortles and Storm Johnson jumped to the NFL, but the opener made it clear that UCF can still compete with Power 5 opposition.
3:30 p.m. ET
No. 6 Georgia at No. 24 South Carolina, CBS
Georgia's visits to South Carolina are almost always must-see TV, although these trips are rarely much fun for Mark Richt's Bulldogs. Even when Georgia has won in Columbia -- and it has lost its past two trips to Williams-Brice Stadium -- the outcome has frequently been in doubt even in the final seconds. Heisman Trophy candidate Todd Gurley should get plenty of work for Georgia in this one.
Arkansas at Texas Tech, ABC
Here's a fun clash of cultures for a national TV audience, which will see Bret Bielema's ground-and-pound face Kliff Kingsbury's passing attack. Texas Tech has a couple of nail-biter nonconference wins on its resume, while Arkansas is coming off a 73-7 drubbing of Nicholls State. The home team is a narrow favorite here, but this could be a good one.
4 p.m. ET
Louisiana-Lafayette at No. 14 Ole Miss, SEC Network
This looked like a sneaky good game before the season, with ULL coming off three consecutive bowl appearances. But the Ragin' Cajuns absorbed a 48-20 beating from Louisiana Tech last week and Ole Miss dominated Vanderbilt in Nashville, so it doesn't look like an upset is in the cards for this one.
Mississippi State at South Alabama, ESPNEWS
This will be the first time an SEC opponent has played at South Alabama and excitement is high in Mobile -- particularly after the Jaguars opened the season with a win and Mississippi State struggled to put away UAB for a while last Saturday. Bulldogs quarterback Dak Prescott and company need to turn in a complete performance with a trip to LSU ahead next week.
6 p.m. ET
Southern Mississippi at No. 3 Alabama, ESPN2
Alabama gets another opportunity to kick around an overmatched nonconference opponent, just as it did last week against Florida Atlantic. The good news for the Crimson Tide, a 48-point favorite, is that most of the starters should be watching from the sideline in the second half, resting up for a visit from Florida next Saturday.
7 p.m. ET
Louisiana-Monroe at No. 10 LSU, ESPNU
Les Miles is a perfect 11-0 against in-state opponents and most of those games have been blowouts, so there is little reason to believe this will be a close contest. That said, the Tigers' secondary should face a reasonable challenge from the Warhawks' no-huddle spread attack.
7:30 p.m. ET
Kentucky at Florida, ESPN
Wildcats running back Jojo Kemp (a native Floridian) poked the bear this week when he made comments about how good it would feel to beat a couple of his former high school teammates -- and current Gators -- and rub it in their faces. Kentucky looks to be a greatly improved team, but it will be a major upset if this game is still close in the fourth quarter, and Kemp's comments probably didn't help the Wildcats' cause.
8 p.m. ET
Tennessee at No. 4 Oklahoma, ABC
As with Kentucky, this is a major measuring-stick game for an improving Tennessee team -- going on the road to face an opponent that virtually nobody expects the Volunteers to challenge. Butch Jones' Vols have been impressive so far, but their inexperience along the line of scrimmage will be their undoing in this one.
9 p.m. ET
Rice at No. 7 Texas A&M, ESPN2
For the second straight Saturday, the Aggies can help SEC viewers get to sleep by drubbing an in-state opponent in a late-night matchup. Rice, a 31-point underdog, might put up more of a fight than Lamar did in losing 73-3 to Texas A&M a week ago, but it won't be much more of one. Kenny Hill and the Aggies win big again.