Earlier, the Red Sox announced that catcher Jarrod Saltalamacchia, whose errant throw led to the Cardinals' walk-off victory in Game 3 on Saturday night, would be replaced in the lineup by David Ross.
Saltalamacchia, who is 0-for-6 in the World Series and is hitting .188 in the postseason, had caught Clay Buchholz's previous three playoff starts this year. Saltalamacchia has struck out 19 times in 32 postseason at-bats.
"We're looking to get some spark, get some offense going," manager John Farrell said before Sunday's game. "That's why David is in there today."
Ross started Game 1, going 1-for-4 with a run scored.
Also in the lineup for the Red Sox as they sought to even the Series at 2-2 was shortstop Stephen Drew, who has been playing great defensively but hitting just .091 for the postseason. One of Drew's four playoff hits came in Game 1, when a harmless popup fell in front of the mound when Cardinals starter Adam Wainwright unexpectedly backed off it.
"If we, again, would be able to guarantee an uptick in offensive production elsewhere ... you've got to prioritize one over the other, and the constant has been his defense," Farrell said of Drew.
For the Cardinals, Allen Craig was sore a day after his baserunning adventure to end Game 3 but was expected to be available.
St. Louis manager Mike Matheny said Sunday that X-rays showed no additional injury to Craig.
Craig served as the designated hitter the first two games, his first action since spraining a ligament in his left foot on Sept. 4.
Information from The Associated Press was used in this report.