Daniel Ponce De Leon to fight May 4

When there's a really big fight in Las Vegas, the promoter typically will put on a smaller card the night before to piggyback off of it.

That is what Golden Boy Promotions will do May 4, the night before the Floyd Mayweather Jr.-Miguel Cotto mega pay-per-view card at the MGM Grand.

Golden Boy announced Friday that former junior featherweight titlist Daniel Ponce De Leon will square off with Eduardo Lazcano in a matchup of Mexican countrymen on Cinco de Mayo weekend at the Hard Rock Hotel & Casino.

Ponce De Leon (42-4, 35 KOs) and Lazcano (24-2, 11 KOs) will meet in a regional junior lightweight title bout scheduled for 12 rounds.

The card, which will air live on Fox Sports Net and be simulcast in Spanish on Fox Deportes (11 p.m. ET), also will feature Las Vegas junior middleweight Ishe Smith against Derrick Ennis in a scheduled 10-rounder.

Ponce De Leon, 31, went 0-for-2 in 2011, losing a controversial 10-round decision to Adrien Broner, who went on to win a junior lightweight world title, and an eight-round technical decision to undefeated former unified featherweight titlist Yuriorkis Gamboa. But Ponce De Leon rebounded for a sixth-round knockout of Omar Estrella on Jan. 21.

Lazcano, 26, a southpaw like Ponce De Leon, won all three of his bouts in 2011 after dropping a 10-round decision to Nery Saguilan in October 2010.

The 33-year-old Smith (22-5, 10 KOs), a one-time fringe contender and participant in first season of "The Contender" reality series, has lost two of his past three fights, but also has not fought since a second-round knockout win against Alexander Pacheco Quiroz in November 2010.

Ennis (23-3-1, 13 KOs), 31, of Philadelphia, has won 12 of his past 13 bouts, although he was knocked out in the second round by Giorbis Barthelemy two fights ago.

Ennis also won a decision against streaking Gabriel Rosado in 2010.