Vegas vs. FPI: Week 10 CFB disagreements

How will Ohio State react coming off of a big loss to Purdue followed by a bye week? Facing Nebraska could be the major shot in the arm the Buckeyes need heading into the home stretch of the season. Zach Bolinger/Icon Sportswire

Although the betting markets and college FPI often have similar opinions about the odds of many college football games, every week there are a few cases where ESPN's model starkly disagrees with Las Vegas.

Each week, we'll point out discrepancies in game predictions and dive into what is causing that difference.

Season record: 22-13-1 (last week: 2-2)

All lines are from the Westgate Las Vegas SuperBook.

Nebraska Cornhuskers at No. 10 Ohio State Buckeyes (-18)

12 p.m. ET, Saturday

FPI prediction: